Christos Pliotas is a Reader in Structural Biology of Membrane Proteins in the School of Biological Sciences at the University of Manchester. He is the Director of the BioEmPiRe Centre for Structural Biological EPR Spectroscopy, an affiliated member of the Manchester Institute of Biotechnology and an elected Fellow of the Royal Society of Biology. His interdisciplinary group, comprising over 12 members from more than seven countries worldwide, focuses on elucidating the structure, function, and dynamics of integral membrane proteins. These include mechanosensitive ion channels, multidrug transporters and outer membrane proteins, all of which are antimicrobial targets in bacterial infections. Christos’ research integrates advanced structural biology methods, including Electron Paramagnetic Resonance (EPR) spectroscopy, electrophysiology, and cryo-Electron Microscopy (cryo-EM), combined with computational modelling and Molecular Dynamics (MD) simulations. Recent work from his lab has been published in Nature Comms, Nature Protocols, PNAS, eLife, Angewandte Chemie, and Nature SMB.
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