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Ingo Ebersberger is a professor for Applied Bioinformatics at the Goethe University Frankfurt, and he is affiliated also with the Senckenberg Biodiversity and Climate Research Centre in Frankfurt (S-BIKF). He is a Molecular Biologist by training who moved into the field of Bioinformatics after completion of his PhD. His main interest is the change of genes and of their activities over evolutionary time scales, and how this relates to the phenotypic characteristics of individual species. The Ebersberger group develops models and algorithms for biosequence analysis and applies these tools in comparative genomics studies across large species collections. They characterize changes in a species’ gene setranging from gains and losses of gene clusters down to modifications on the sub-domain level of the encoded proteins, often in the context of organismic symbiosis. In bacteria, the group seeks to identify the molecular basis of pathogenesis and virulence.